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Introduction The first reports about a plant glutathione S-transferase enzyme (GST, EC 2.5.1.18) appeared in 1970, when it was revealed that a GST catalyzed the detoxification of the herbicide atrazine by its conjugation to the endogenous tripeptide glutathione (GSH, -L-glutamyl-L-cysteinyl-glycine) in sorghum and maize plants (Frear and Swanson, 1970)

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The mechanism is scientifically sound and consistently supported by animal data, but human efficacy and safety have not been established through clinical trials

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Food colour additives: a synoptical overview on their chemical properties, applications in food products, and health side effects