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Additionally, quercetin prevents the upregulation of NO and iNOS in PC12 cells and suppresses the production of proinflammatory genes (IL-1, COX-2, and TNF-) in zebrafish [117]

mentions the modest clinical effects of L-glutamine therapy on sickle cell crises, the lack of understanding of mechanism of action, its high cost, and possibly poor tolerance)

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Copper is a pivotal trace element and a biologically active cofactor within the human body, exerting a critical influence on a multitude of physiological processes, including mitochondrial respiration, biosynthetic pathways and antioxidant defense mechanisms (1)