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This mechanism makes L-carnitine especially valuable during aerobic exercise, when the body taps into fat stores for sustained energy

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346,347,348 The first is the exogenous route, in which the NADs are directly introduced into the obtained exosomes via electroporation, co-incubation, sonication, extrusion, and freeze-thaw cycling

Additionally, the area under the curve (AUC) for CU in rats was found to be 3.6 0.6 min/g/mL following oral administration of 500 mg/kg, and only 7.2 1.2 min/g/mL after intravenous administration of 10 mg/kg, further indicating poor absorption characteristics (Yang et al., 2007)

PMID: 10501046