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However, the correlation with BMI, Waist circumference, Glucose, HbA1c, Insulin, HOMA-IR index, triglycerides (TG), total cholesterol (TC), Low-density lipoprotein-cholesterol (LDL-C), Systolic BP, C-reactive protein (CRP) and Serum folate was insignificant or weak

By reducing adipose tissue mass, improving lipid profiles, and enhancing mitochondrial function, NNMT inhibition addresses multiple pathways involved in metabolic syndrome development

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Together, these findings illustrate definitive spinal cord injury with very small spontaneous improvements in functional loss