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doi: 10.1089/dna.2018.4541 211 ArbitmanLFurieRVashisthaH

Moras M, Hattab C, Gonzalez-Menendez P, Fader CM, Dussiot M, Larghero J, et al

Cumulative evidence demonstrates that A and tau are neurotoxic and can trigger a cascade of neurodegenerative processes ending in neuronal death, suggesting that overproduction/accumulation of A and tau in vulnerable brain regions is the primary influence driving AD pathogenesis (Hardy and Selkoe, 2002