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In summary, these studies in regenerating sensory organs suggest that active Wnt/-catenin signaling can increase the extent of mitotic hair cell regeneration (Figure 4), yet the ability of activating Wnt/-catenin signaling alone to renew proliferation and hair cell regeneration observed in the neonatal, immature mammalian cochlea appears limited in the mature, mammalian cochlea

First, the two core mechanism papers establishing the HGF/c-Met story (Kawas 2012, PMID 22129598

The scientific studies of these experimental drugs were never large enough or long enough to establish a clear safety profile, so all we are left with are vague reassurances from tiny studies and testimonials from YouTubers and TikTokers

Journal of Neural Transmission, 113(6), 855-868

Breast J