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For instance, if we examine the deposition trends for spray administration through the right nostril of Subject 2 for the laminar regime inhalation (i.e., at 15 L/min), the peak nasopharyngeal deposition for IU is 46.5% for 13 m drug droplets (Figure 6H), while the peak deposition for CU is only 0.53% for 14 m drug droplets (see again Figure 6H and the corresponding zoomed-in visual for the CU delivery trends in Figure 6K)

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Empirical therapy for mild CAP often comprises a macrolide, in locations with high rates of macrolide resistance, particularly in patients with comorbidities, a respiratory fluoroquinolone or a combination of a beta-lactam and a macrolide is suggested [21]

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