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Nature, 508(7495), 258-262

With tremendous marketing and promotion, Nexium became the third best-selling drug of the past quarter-century

This suppression of cytokine gene expression, which was observed both in vivo and corroborated in vitro in human hepatoma cells, underscores a key mechanism through which DHA attenuates hepatic inflammation and contributes to the amelioration of NAFLD ( Beyond cytokine suppression, DHA also exerts its protective effects by targeting specific inflammatory signaling complexes

For example, native restriction enzymes generally are not expressed abundantly and must be purified free from many other nucleases that wild-type organisms produce

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