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Neuromelanin-sensitive magnetic resonance imaging features of the substantia nigra and locus coeruleus in de novo Parkinsons disease and its phenotypes

REDEFINE 3 evaluates cardiovascular outcomes (~7,000 participants, event-driven)

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At the same time, the binding of p-CREB and CBP to Bdnf promoters also increased, implying the activation of Bdnf transcription

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