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In particular, exposures among the controls could have been underestimated if exposure diminished with time and if the selection of controls did not fully represent the actual distribution in the past (e.g., through changes in the populationimmigration or emigration)

The coated Dynabeads with antibody may be reused several times using mild elution methods like low pH or high salt concentration

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It has been observed that repeated doses of DCA resulted in loss of GSTZ1-1 protein and activity, probably due to post-translationally modifications of the enzyme 85