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Injections may cause redness, swelling, or mild irritation at the site of administration

characteristic of intrahepatic cholestasis of pregnancy Hepatomegaly / splenomegaly hepatosplenomegaly suggests hemolytic anemia or portal hypertension Neonatal-specific: poor feeding, lethargy, high-pitched cry, hypotonia early warning signs of acute bilirubin encephalopathy

Its extreme short half-life (minutes) means intranasal or oral routes without modification are ineffective due to rapid degradation

Suryavanshi SV, Kulkarni YA (2017) NF-kappabeta: a potential target in the management of vascular complications of diabetes

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