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Lonsdale D, Shamberger RJ, Stahl JP, Evans R

Trends Pharmacol Sci

As expected, hTrxR1 W114A,U498C did not have detectable activity with hTrx1 C73S (Table 2)

In certain embodiments, one or more reactive functional groups of one or more amino acids of the amino acid-comprising conjugation partner are unprotected