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Its abnormal activation not only affects immune system function but also participates in the damage process of important organs such as the lungs and heart, suggesting that targeted regulation of the mTOR pathway may be a new therapeutic strategy for multi-organ protection in sepsis

High density lipoproteins induce cell cycle entry in vascular smooth muscle cells via mitogen activated protein kinase-dependent pathway

When you introduce a compound at the exact same time, under the exact same conditions, every single day, you create a predictable physiological response

Del Rey MQ, Mancias JD

Ferroptosis agonists directly or indirectly affect glutathione peroxidase (GPXs) through various pathways, leading to a reduction in antioxidant capacity, accumulation of ROS, and ultimately oxidative cell death (115, 116)