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The target peptide is a crucial intestinal transport protein, is responsible for the absorption of dipeptide and tripeptide during the digestive process

T.WallachT.ReischlS.OehmkeS.et al (2009)

Importantly, several core mitophagy regulators are organized at or influenced by mitochondria-associated ER membranes (MAMs), indicating that mitophagy-directed therapy may also act, at least in part, through remodeling of organelle contact sites rather than through mitochondria alone

Moreover, in mantle cell lymphoma (MCL) which is resistant to genotoxic agents vincristine, iCRTs eliminated MCL-initiating cells very well

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