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Both showed efficacy but neither completed the full approval process

l-carnitine can increase antioxidant and mitochondrial functions in human osteoblast-like cells, via up-regulation of osteopontin, bone sialoprotein, transcription factor Sp7(Osterix), and RUNX2 genes

doi: 10.1016/j.ijrobp.2017.05.035 96 ChaoMHoHChanYTanAPhamTBoltonDet al

10.21037/apm-21-3472 Summary Keywords acute pancreatitis, traditional Chinese medicine, NLRP3, inflammation, antiinflammatory Citation He X, Xia J, Chen Q, Huang Z, Lu J and Ren Y (2025) An overview of current research on the modulation of NLRP3 inflammasome by traditional Chinese medicine to combat acute pancreatitis