glutathione-responsive prodrug

glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of PDF) Glutathione responsive iNOS inhibiting

Name: glutathione-responsive prodrug GSH-triggered drug release and the responsive mechanism of PDF) Glutathione responsive iNOS inhibiting
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SKU: 85438404997
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PDF) Glutathione responsive iNOS inhibiting polymeric prodrug for targeted Inhibition of angiogenesis Glutathione responsive prodrug conjugates for image guided combination in cancer therapy ScienceDirect Construction of glutathione responsive paclitaxel prodrug nanoparticles for image guided targeted delivery and breast cancer therapy RSC Advances (RSC Publishing) DOI:10.1039 D4RA00610K Redox Responsive Polyprodrugs: Recent Innovations in Reduction and Oxidation Responsive Drug Delivery Systems Chemistry of Materials Dual pH redox responsive hyperbranched polymeric nanocarriers with TME trigger size shrinkage and charge reversible ability for amplified chemotherapy of breast cancer Scientific Reports

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Description

Taking advantage of the fact that they can be reduced by thiols that exist in the cell cytoplasm, such as glutathione, ADCs have been engineered to be conjugated to the disulfide linkers that remain stable in the circulation and selectively release drugs in the cytoplasm

10.3892/ijmm.2015.2412 67 LiuM.LiuS.ZhangQ.FangY.YuY.ZhuL.et al (2021)

Kheirouri S, Alizadeh M

Emerging CAR-macrophage (CAR-M) platforms, exemplified by anti-HER2 CAR-Ms, not only mediate the direct phagocytosis of tumor cells but also potentiate antigen presentation and pro-inflammatory cytokine release (187)