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J., Mancuso A., et al., Myc Regulates a Transcriptional Program that Stimulates Mitochondrial Glutaminolysis and Leads to Glutamine Addiction, Proceedings of the National Academy of Sciences of the United States of America 105, no

161 Relationship between the microbiota and metabolism Generally, cancer cells undergo extensive metabolic reprogramming to accommodate the demands of rapid proliferation, survival in hostile microenvironments, and metastasis

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164 Crucially, mTORC1 also acts as a primary regulator of eEF2K, 165 exemplified by the numerous downstream targets of AMPK that are directly phosphorylated by mTORC1 or S6K1, to counteractively modulate their functions in relation to AMPK phosphorylation

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