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Rocha-Gomes, A., Escobar, A., Soares, J

.,XingL,TangY,LiLTaoXROS in hepatocellular carcinoma: What we know.2023;744:109699

doi: 10.3389/fimmu.2022.821533 140 SivoriSCarlomagnoSPesceSMorettaAVitaleMMarcenaroE

Some major drawbacks associated with the clinical application of such NPs are their poor ability to cross the BBB and the inconsistent clinical efficacy of GDNF in PD treatment