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The authors compare multiple senolytic strategies including FOXO4-DRI, dasatinib plus quercetin, navitoclax, and fisetin, evaluating mechanisms of action, selectivity profiles, and safety considerations for each approach

Activation of Telomerase Reverse Transcriptase (TERT) Downregulation of HER-2/neu Expression Biological Activity Epithalon has been shown to increase lifespan in rodent models, reduce spontaneous and induced tumor formation, stabilize the genome by reducing chromosomal aberrations, and modulate immune cell proliferation