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Laboratory breeding of the short-lived annual killifish Nothobranchius furzeri

pneumoniae [3, 8, 25]

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This is the theoretical basis for endogenously supplied gamma-glutamylcysteines ability to raise GSH levels, as being the product of the GCL enzyme, it can be taken up by cells intact, where it feeds directly into glutathione synthase to be converted to glutathione, effectively bypassing the dysfunctional GCL

Studying humans is therefore urgently needed to determine the doseeffect relation of DR interventions in human cancer treatment