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Abbreviations ALI: Acute lung injury ACE: Angiotensin converting enzyme ARDS: Acute respiratory distress syndrome COPD: Chronic obstructive pulmonary disease CF: Cystic fibrosis CFTR: Cystic fibrosis transmembrane regulator CHD: Coronary heart disease IL: Interleukins IPF: Idiopathic pulmonary fibrosis MMP: Matrix metalloproteinase MAPK: Mitogen-activated protein kinase NF-kB: Nuclear factor-kappa B ROS: Reactive oxygen species RCT: Randomized clinical studies SARS-CoV-2: Severe acute respiratory syndrome- corona virus-2 TB: Tuberculosis TGF-: Transforming growth factor-beta TNF-: Tumor necrosis factor-alpha Th: T-Helper cells TLRs: Toll like receptors References Maes K, Serr J, Mathyssen C, Janssens W, Gayan-Ramirez G

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Transcription factor RFX1 is ubiquitinated by E3 ligase STUB1 in systemic lupus erythematosus