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The inhibition of 3.7 nM TGR with 250 M inhibitor, 100 M NADPH, and a 15 min pre-incubation at RT was measured to compare to the inhibition after the jump dilution

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It functions by donating the hydrogen atom to fatty peroxyl radicals and disrupting the lipid peroxidation process

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Iron homeostasis is central to ferroptosis regulation, with disruptions significantly influencing cell death

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