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Additionally, COP1 can assemble into an octameric structure by intertwining coiled-coil domain interactions

2016 PMC4955757 Roberts, MA

Although genetic circuits offer exciting possibilities for programming biological behavior, 712 efforts to implement circuits in vivo often yield unpredictable results

The different mechanisms -- direct scavenging (glutathione), strategic reserves (ergothioneine), and catalytic cycling (PQQ) -- ensure systems-wide coverage across various types of oxidative stress