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Elevated GLS expression is also associated with different cancer types, including glioblastoma and pancreatic cancers, thereby encouraging investigation of more targets should current clinical trials prove successful [28, 61]

Consistently, SOD1 G93A transgenic mice exhibited ferroptotic features and neurotoxic glial activation resembling those observed in ALS patient spinal cords and in vitro models

Moreover, the role of variation in drug metabolizing enzymes between different individuals and its possible impact on the hepatic injury induced by these drugs is discussed here

doi: 10.1016/j.ejmg.2013.10.002

Neutrophils as critical orchestrators of chronic inflammation