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Also, elevated levels of trans-fats have been found in the adipose (fat) tissue of people with Crohn's disease (Heckers 1988

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4.2 Humoral pathways The humoral pathway represents a key route through which gut-derived factors may influence central nervous system processes in PD

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The molecular mechanisms and signaling pathways underlying these benefits are complex and multifaceted, encompassing direct interactions with gut microbiota, strengthening of gut barrier function, modulation of immune responses, and attenuation of systemic inflammation