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Check blood pressure (hypotension can cause compensatory HR increase)

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For patients already on injections, this is what the dosage translation looks like: 0.250.5 mg injection start 4 mg or 9 mg pill for 30 days 1.0 mg injection start 9 mg pill for 30 days 1.7 mg injection start 9 mg pill, then titrate to 25 mg after 30 days 2.4 mg injection (max dose) stop injection, wait 7 days, then start 25 mg pill Note: There is *no direct milligram-to-milligram equivalence* between injections and pills

For a researcher who wants to explore this combination in vitro or preclinically, it is precisely a good topic for original research, not an established fact