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We replace any folic acidcontaining supplements with L-methylfolate (or sometimes folinic acid) and a high-quality B-complex that uses active forms

Haruno Mizuta for her technical assistance in conducting experiments for the supplementary figures

The gasdermin-N domains of the GSDMD, GSDMA3 and GSDMA can bind membrane lipids and cardiolipin, and execute pore-forming activities for pyroptosis [149]