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Unlike sepsis, where treatments are primarily directed against LPS-induced inflammatory responses (e.g., anti-endotoxin antibodies), SAP-induced glycocalyx damage is predominantly driven by pancreatic enzyme activation (e.g., trypsin) and intestinal endotoxin release

There is no evidence from long-term use in patients with pernicious anemia that cyanocobalamin is carcinogenic

Wahab S, Anwar AI, Zainuddin AN, Hutabarat EN, Anwar AA, Kurniadi I

But each of the substances would be reviewed for potential inclusions at the PCAC either during the July 2026 meeting or before February 2027

Oxidative stress may also affect dermal papilla cells and other structures around the hair root