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3b, gels 3 and 4)

Most, but not necessarily all, cultured metaphase chromosomes show excessive and abnormal breaks

It is generally accepted that excess cytosolic copper is tightly bound by the metallothioneins, preventing the existence of free, unbound copper ions

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Low molecular weight compounds, such as antioxidative vitamins (A, C, and E) and glutathione, react with ROS and convert them to harmless compounds