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Keywords: Cuprizone, Multiple Sclerosis, Demyelination, Oligodendrocytes, Inflammation, Cell death, Astrocytes, Microglia, CNS Background Multiple Sclerosis (MS) is a chronic neurological disorder characterized by the loss of myelin or demyelination

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In a study of 225 normal and pre-diabetic patients, MOTS-c levels were considerably lower in T2D than controls subjects

We also thank Alicia Thompson, formerly the head of the Electron Microscopy and Microanalysis Center at USC (now retired), for taking the photographs shown in Fig