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It is noteworthy that DBS is not suitable for all patients, as its efficacy and safety are highly dependent on precise target localization, individualized parameter programming, and meticulous postoperative management

18 mTORC1 integrates signals from nutrients and growth factors to regulate various anabolic processes, including protein synthesis, nucleotide production, lipid biosynthesis, and glycolysis, while inhibiting catabolic processes such as autophagy by phosphorylating ULK1/2 and sequestering lysosomal enzymes

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Around 30% of patients with a diagnosed migraine suffers from the so-called migraine with aura [7,8]

10.1007/s10522-024-10099-6 68 XuY.LiuX.GuanJ.ChenJ.XuX