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Murray SE, Polesso F, Rowe AM, et al

In the cultures treated with B12, 45 and 74 out of these 90 pathways were still differentially regulated in MOD and SEV groups, respectively, although with a minimum 20% difference in Z-scores relatively to their untreated condition

Additional adverse effects documented in the research include QT prolongation (a heart rhythm change), skin reactions including photosensitivity and rarely Stevens-Johnson syndrome, weight and body composition changes, and a possible association with cataracts on long-term use

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injections of NPY into the lateral ventricle at 0, 8, and 23 h post-preswim increased swimming and reduced immobility in a dose-dependent manner, mimicking the effects of serotonergic antidepressants [143]