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Fibroblasts derived from human ACLs, seeded in fibrin gels, and treated with peak physiologically relevant estrogen levels ( i.e ., 34 d before ovulation) have reduced mechanical properties (ultimate tensile stress, modulus) and LOX activity, but no changes in collagen content

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doi:10.1186/1751-0759-2-3 Crawford C, Wallerstedt DB, Khorsan R, Clausen SS, Jonas WB, Walter JA

Currently, FCS is used for the analysis of the photodynamic properties of fluorescent dyes, study of translational and rotational diffusion, in various binding assays, as well as investigation of conformational fluctuations of biomolecules, and even analysis of living cells (e.g., counting fluorescence particle in vivo , probing cellular organelles, and analysis of nuclear structure) (Maiti et al., 1997