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reuteri , 15007, was shown to increase the TER in IPEC-J2 by only 8% after 10 h of treatment and that was associated with a mild increase in expression of claudin-1, occludin, and ZO-1

Looking ahead, endoscopic interventions may become a successful method for treating postoperative gastric leaks and gastrocutaneous fistulas, as they are already well-established for complications following laparoscopic sleeve gastrectomy and gastrostomy

The potential of these polyphenolic applications has already been identified, as there are already some studies on the application of polyphenols in food products like bacterial biofilm inhibition, edible coatings, and smart packaging [122,123]

Some research has even explored a possible link between B-12 deficiency and depressive symptoms, which well explore further in later sections