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To isolate neutrophils, bone marrow cells were subjected to red blood cell lysis and stained with fluorochrome-conjugated anti-mouse antibodies to CD11b (Mac-1, BD Biosciences 553310

Pathways and regulation of bacterial arginine metabolism and perspectives for obtaining arginine overproducing strains

Here, we reviewed overexpressed YAP1 stimulates the production of cytokines, leading to increased infiltration of macrophages, MDSCs, and Tregs, ultimately resulting in an immunosuppressive TME that promotes tumor initiation and progression