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Physiological and pathological functions of NADPH oxidases during myocardial ischemiareperfusion

Raghu G, Anstrom KJ, King TE Jr, Lasky JA, Martinez FJ

[DOI] [PubMed] [Google Scholar] Wostyn P, De Groot V, Van Dam D, Audenaert K, De Deyn PP, 2016

In fact, MitoQ has been used in a range of in vivo studies, in rats and mice, and in two phase II human trials demonstrating that it can be safely delivered to patients with promising results, lending further support that mitochondria-targeted antioxidants may be applicable to a wide range of human pathologies that involve mitochondrial oxidative damage (Smith and Murphy, 2010)

Resuscitation 49:307314 Kaur C, Srinivasan KN, Singh J, Peng CM, Ling EA (2002) Plasma melatonin, pinealocyte morphology, and surface receptors/antigen expression on macrophages/microglia in the pineal gland following a high-altitude exposure