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207 Platinum-resistant ovarian cancer cells and tissues are more likely to form spheroids and have increased level of the Wnt receptor frzzled 7 (FZD7)

It can be flat

Studies reported that CSCs invariably hijack the pluripotent or oncofetal drivers like OCT4, SOX2, KLF4, MYC, SALL4, FOXM1, Wnt/-catenin, Hedgehog, Hippo, TGF- of ESCs [99]