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Additionally, some people are predisposed to B12 deficiency as certain conditions exist where the body does not have the ability to absorb Vitamin B12 (Shipton & Thachil, 2015)

Without these data, even a positive skin outcome would be difficult to attribute to a specific mechanism, and a safe cumulative-dose ceiling could not be defined

doi: 10.1016/j.jsxm.2017.07.005 67 LiangLZhengDLuCXiQBaoHLiWet al

doi: 10.1159/000102047

Statistical analysis of the experimental findings included a trial product estimate that evaluated the treatment effect in the participants based on data that was collected through the 32 week treatment period