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For perspective, that level of weight loss was previously achievable only through bariatric surgery

Conversely, SCFAs, as key microbial metabolites, can reverse IEC damage: SCFAs interact with G-protein-coupled receptors (GPCR41 and GPCR43) on IECs to induce enteroendocrine hormone release, thereby modulating disease processes (76)

17Beta-estradiol prevents retinal ganglion cell loss induced by acute rise of intraocular pressure in rat

In particular, mass spectrometry-based proteomic methods have emerged as a powerful means to identify and quantify cysteine oxidation sites on a proteome scale

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