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The redox state shifted towards oxidation in peroxisomes, organelles associated with the detoxification of ROS and H 2 O 2 from photorespiration, during 22 h of darkness, whereas in chloroplasts, which are organelles associated with glutathione synthesis, the redox state was specifically affected by short-term excess light (3 h at 600 mol m 2 s 1 ) (Bratt et al

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Photo after 5 months of treatment After three months, there was little improvement, so the dose of isotretinoin was increased

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