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The idea was further validated by inhibiting glutathione synthesis by BSO where Sp administration caused GSH to increase by ~1.5 fold with concomitant reduction in GSSG (Fig

Preoperative oral administration of L-theanine and cystine regulates the oxidation-reduction cycle of GSH, decreases the inflammatory cytokines, alleviates the infiltration of white blood cells, and reduces the damage of inflammatory injury to the body tissues, thus improving the survival rate after intestinal ischemia-reperfusion in a dose-dependent manner [32]

Shree Harini, K

Ponesimod protects against neuronal death by suppressing the activation of A1 astrocytes in early brain injury after experimental subarachnoid hemorrhage