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As expected GPP3 was observed bound within the hydrophobic pocket of VP1, in an essentially identical conformation to that previously observed for this compound bound to plant expressed PV3-SC8 18 (Fig

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12 In 1999, the results of a large trial including 305 patients was published, showing control of menorrhagia in 86% of the cases at 3 months and 92% at 12 months