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Description

Recent advances in understanding intestinal stem cell regulation

The batch of the ARPE-19 cells used in this study was validated using short tandem repeat (STR) analysis by Cobioer Biosciences (Nanjing, China)

In all our previous murine studies we have used short cycles (1014 days) of very low subcutaneal doses (20 g/kg/day) after carefully assessing its circulating concentrations and using the minimum amount that was sufficient to adequately restore physiological values of the molecule

Pretreatment with black cumin seed ethanolic extract (800 mg/kg) exhibited a promising cardioprotective action against isoproterenol-induced myocardial infarction by improving cardiac biomarkers and antioxidant status [144]

In a transgenic mouse expressing low GSH levels (Gclm KO), we found reduced number of prefrontal and hippocampal PV-immunoreactive interneurons together with diminished high-frequency neuronal synchronization [81, 82], reduced number of PV-immunoreactive neurons in thalamus reticular nucleus together with altered firing properties [56], thus demonstrating the functional consequence of a redox dysregulation