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Skin discoloration happens due to excessive melanin production

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Getting adequate sleep was shown in a study of Japanese adults that found that sleep deprivation may increase the formation of AGEs.[ref] Men with sleep apnea have higher circulating levels of AGEs and insulin resistance.[ref] Plus, sleep apnea also increases RAGE.[ref] Focusing on a regular sleep schedule, fixing sleep apnea if you have it, and prioritizing a strong circadian rhythm may be as important as diet when it comes to AGEs and RAGEs