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doi:10.5152/npa.2016.18143 Wei W, Sayyid ZN, Ma X, Wang T, Dong Y

For each category, Clinical questions (CQs) were established and the literature was searched, reviewed, extracted, selected, and examined

75,76 Although other sources of oxidants (H 2 O 2 ) than the electron transport chain have been identified in relation to fatty acid metabolism within mitochondria, 77,78 the formation of peroxynitrite as the critical oxidant for mitochondrial dysfunction requires superoxide, which is generated by the electron transport chain