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Translation initiation at the 5AUG results in the generation of a GPx4 isoenzyme, that is targeted for mitochondrial import (mitochondrial GPx4, m-GPx4)

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Acknowledgements This work was supported by funds from Natural Science Foundation of China (22377033, 22377037, 22577038, 82473109), the Science and Technology Program of Guangdong Province (2023B1515120023, 2025A0505080018, 2024A1515013002, 2023A0505050149), Guangdong Basic and Applied Basic Research Foundation (2023B1515040016, 2025A1515012357, 2024A1515013266, 2026B1515020070)

Methods Antibodies and chemical reagents The following antibodies were used in this study: Annexin V FITC-conjugated (Molecular Probes), mouse fibroblast specific protein-1 (Abcam), mouse CD31 PE-conjugated (Militenyi), mouse CD14 PerCP Cy5.5-labelled (BD Biosciences), mouse B220 PE-Cy5-labelled (BD Biosciences), and human CD44 APC-conjugated (Militenyi) antibodies