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(2002) Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice

GSSG, exported via MRP-1, may be recognized as a DAMP and result in the activation of defense responses

In patients with low-grade gliomas and patients with secondary glioblastoma, the proportion of IDH1 mutations can reach about 70%, but there is currently no selective treatment for IDH1 mutant gliomas

Many people experience fluctuating severity during this period, with some days better than others

To evaluate reduced TGR, 500 M NADPH was added