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Table of Contents Many people today experience dull skin, pigmentation, tanning, uneven skin tone, and tired-looking skin due to stress, pollution, sun exposure, and unhealthy lifestyle habits

All real-time PCRs were performed three times and all changes in gene expression were reported as multiples of increases relative to the control while GAPDH was used as an internal control and relative gene expression between the experimental groups were determined using MxPro software

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Concentrations decline sharply with age: plasma levels drop from roughly 200 ng/mL at age 20 to under 80 ng/mL by age 60