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In response to the detection of microtoxicants, human bronchial epithelial cells produce a variety of cytokines, chemokines, and other signaling molecules, including interleukins (IL-1, IL-1, IL-6, IL-8) and granulocyte-macrophage colony-stimulating factor (GM-CSF), which contribute to the activation of airway inflammation ( Figure 1) [9, 14]

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