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Occupational exposure to carcinogens in industries such as chemicals, dyes, rubber manufacturing, and petroleum processing is the second leading risk factor for urothelial bladder cancer (UBC) after smoking, accounting for approximately 20% of cases, primarily in industrial regions

This study convincingly shows how metastatic routes may shape the propensity of cancer cells to succumb to ferroptosis depending on the differing microenvironment in lymph or blood

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Special focus on the molecular mechanisms involved

Propofol inhibits ferroptotic cell death through the nrf2/gpx4 signaling pathway in the mouse model of cerebral ischemia-reperfusion injury